A United Nations watchdog called on Mexico on Friday to probe and prosecute alleged complicity of state forces in "disappearances", including a notorious case of 43 students believed murdered last year, Daily Mail reported.
Mexico's delegation told the UN Committee on Enforced Disappearances at a review last week that 11,300 people were unaccounted for.
Amnesty International said in a statement that more than 22,600 had gone missing in the past eight years amid "a huge problem of impunity".
In their findings, the committee's 10 independent experts said they had received information that "illustrates a context of generalized disappearances in a great part of the territory (of Mexico), many of which could be qualified as enforced disappearances".
"Enforced disappearances" are those linked to detention or abduction by state agents such as police or security forces, or their allies, who conceal the victim's fate.
Mexico's Attorney General Jesus Murillo has said there is no doubt that the 43 students were murdered last September and their remains incinerated and dumped into a river in the nearby town of Cocula.
Officials say they were abducted by corrupt police officers, who handed them over to a local drug gang. The former mayor of the southwestern town of Iguala has been arrested.