
U.S. researchers said Wednesday they have developed a new vaginal gel that might help protect women from HIV even it's applied three hours after sex. Vaginal gels containing antiretroviral drugs are important for HIV prevention but are all designed to be applied by women before sex, which can interfere with sex practices and limit their use, the researchers wrote in their Science Translational Medicine paper. They believed a gel that can be applied after sex would be more practical because it will give women more control and would require less preparation before sex and less partner acceptance. The gel, developed by researchers of the U.S. Centers for Disease Control and Prevention, contains the anti-HIV drug raltegravir. Using a macaque model to assess efficacy, the researchers found applying the gel 30 minutes before exposure protected two of three macaques from SHIV, a combination of HIV and a related monkey virus. More importantly, the gel was equally effective when applied after exposure. The researchers said five of six macaques treated with the gel three hours after SHIV exposure remained uninfected after 20 virus challenges and the 10-week follow-up period. The researchers noted these observations require confirmation in larger numbers of animals. "In conclusion, we show preclinical in vivo data that support the use of topical integrase inhibitors for HIV prevention," they said. "This study supports evaluation of this class of drug for HIV prevention ... (and) further evaluation of postcoital modalities in women for enhanced acceptability and compliance."
GMT 18:35 2018 Thursday ,11 January
Syrian refugee sets himself ablaze at UN office in LebanonGMT 18:48 2018 Tuesday ,09 January
Novo Nordisk woos Belgian nano-drug makerGMT 17:54 2017 Wednesday ,27 December
Medical evacuations begin from besieged Syria rebel bastionGMT 12:14 2017 Monday ,25 December
MoHAP successfully conducts cochlear implant operationGMT 18:24 2017 Sunday ,24 December
Palestinian conjoined twins arrive in RiyadhGMT 19:05 2017 Monday ,18 December
new! magazine names fitness & food editorGMT 17:03 2017 Wednesday ,29 November
Spain reports case of 'mad cow disease'GMT 14:05 2017 Saturday ,11 November
EU can't agree on new licence for controversial glyphosate weedkiller
Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2025 ©
Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2025 ©
Send your comments
Your comment as a visitor